Living SLRs and AI in the EU JCA Era: Alignment and Gaps Across PRISMA, Cochrane,
ISPOR, and HTA Guidance
Grieve S, Musat M, Pramanik A, Liu R, Forsythe A
Presenter: Anna Forsythe, MSc, PharmD, MBA
Date: Monday, May 18
Presentation: 10:30am – 11:30am
Poster available after presentation
Poster tour
Evidence-Based PICO Mapping for EU Joint Clinical Assessment (JCA) Using a Real-Time AI-assisted Living Systematic Literature Review (REAL-SLR): An Advanced Non-Small Cell Lung Cancer (NSCLC) Case Study
Comprehensive Real-Time AI-assisted Living Systematic Literature Review (REAL-SLR) Outperform Custom Reviews for Strategic Health Technology Assessment (HTA) and Market Access (MA) Planning: An Advanced Metastatic Breast Cancer (mBC) Example
Validation of an Agentic Large Language Model (LLM) System in the Review Stage of a Real-Time AI-assisted Living Systematic Literature Review (REAL-SLR): a Solution to Instant and Easy access to Clinical Trial Data (CTD)
Living Cost-Effectiveness Sequence Analysis (sequence-CEA) for Chronic Lymphocytic Leukemia (CLL): A Payer-Centric Framework for Dynamic Formulary Decision Making
Discrepancies between guideline recommendations and regulatory approvals in multiple myeloma - importance of evidence stratification of a living systematic literature review (SLR)
Evidence-Based PICO Mapping for EU Joint Clinical Assessment (JCA) Using a Real-Time AI-assisted Living Systematic Literature Review (REAL-SLR): A Metastatic Breast Cancer Case Study
Enabling Health Technology Assessment (HTA) TA Readiness Through Real-Time AI-Assisted Living Systematic Literature Reviews (REAL-SLR): A Breast Cancer (BCa) Case Study
Use of Real-time AI-assisted Living Systematic Literature Review (REAL-SLR) in prostate cancer (PC) enables on-demand access to pivotal clinical trial evidence
Campden R, Jiang X, Sarkisian S, Rege J, Liu R, Forsythe A
Adapting Agentic Large Language Models (aLLM) Trained in Solid Tumors for Systematic Literature Review (SLR) in Hematological Malignancies: Validation in Multiple Myeloma (MM) and Chronic Lymphocytic Leukemia (CLL)
Real-Time AI-Assisted Living Systematic Literature Review (REAL-SLR) Captures a 2025 Standard-of-Care (SOC) Shift Driven by Antibody-Drug Conjugates (ADCs) in Urothelial Carcinoma (UC): Implications for Health Technology Assessments (HTAs)
Campden R, Kasireddy E, Sarkisian S, Liu R, Forsythe A
Validation of an Agentic Large Language Model (LLM) System in the Extraction Stage of a Real-Time AI-assisted Living Systematic Literature Review (REAL-SLR): a Solution to Instant and Easy access to Clinical Trial Data (CTD)
Liu R, Campden R, Liu E, Grayston T, Correa O, Forsythe A
Incorporating real-world evidence (RWE)using aReal-Time AI-assisted Living Systematic Literature Review (REAL-SLR)augments traditional SLRs: Case study in Non-Small-Cell Lung Cancer (NSCLC)
